The Virtual Microscope

Principle Investigators

Joel Saltz, M.D., Ph.D.
Alan Sussman, Ph.D.
Bob Miller
Angelo Demarzo
Mark Silberman
Asmara Afework
Mike Beynon, Ph.D.
Renato Ferreira, Ph.D.
Anthony Wiegering

Related Information

  • Publication List
  • Presentation Slides
  • Active Data Repository Accelerates Access to Large Datasets, NPACI enVision, Volume 14, Number 2, April-June 1998
  • The Virtual Microscope is a client-server system designed to provide a realistic digital emulation of a high power light microscope. The client is an image browser that runs on a user's PC or workstation. The server is responsible for storing, retrieving, processing, and serving the microscope image data and runs on a high performance machine. The raw data for such a system can be captured by digitally scanning collections of full microscope slides under high power. The system is required to provide interactive response times for the standard behavior of a physical microscope. These behaviors include continuously moving the stage and changing magnification and focus. In addition, a software solution can enable new modes of behavior that cannot be achieved with a physical microscope, such as simultaneous viewing and manipulation of one slide by multiple users. The Virtual Microscope is an example of a broader class of applications that manipulate large multi-dimensional datasets. The main difficulty in providing the functionality of the Virtual Microscope is the storage and delivery of the extremely large quantities of data required to allow interactive browsing of a large collection of slides.

     

     


    Department of Computer Science
    The John Hopkins University
    Department of Pathology
    Johns Hopkins Medical Institions